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Research paves way for better drugs for breast cancer

23

Aug

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Health & FitnessBhopal, cell, DBT/Wellcome Trust India Alliance, DNA, drug, epigenetic, gene, growth, hypoxic, IISER, Indian Institute of Science Education and Research, metastasis, OXYGEN, patient, proliferate, protein, RNA, therapeutic, tissue, transcription factor, tumour

Research paves way for better drugs for breast cancer

New Delhi, Aug 23: In a study that could help design better drugs for breast cancer, researchers at the Indian Institute of Science Education and Research (IISER)-Bhopal have identified the mechanism by which breast cancer cells proliferate and spread. The team studied the regulation of a gene called ‘ESRP1’ in breast cancer. They found that there is a difference in the expression of the ESRP1 gene between normal and tumour tissues of breast cancer patients. The gene was expressed more in breast tumour tissues than normal tissues. They then explored the regulatory mechanism behind this. The expression of a gene…

Indian scientists develop artificial enzyme to keep HIV virus in check

New Delhi: People suffering from Human Immunodeficiency Virus (HIV) infection can now hope to have a better quality of life with researchers at the Bengaluru-based Indian Institute of Science (IISc) developing a nano alternative to a natural enzyme that is used to block reactivation and replication of the virus in the host’s immune cells. Made from vanadium pentoxide nanosheets, the new “nanozymes” work by mimicking the natural enzyme called glutathione peroxidase to help reduce oxidative stress levels in the host’s cells, which is required to keep the virus in check. Presently, there is no method available to completely eliminate HIV…

Study kindles new hope for a cure for Parkinson’s Disease

New Delhi: Efforts to find a cure for Parkinson’s Disease is expected to get a big boost with researchers at the Indian Institute of Technology-Madras finding that energy deficiency in certain cells in the human brain could be a major cause for the development of the neurodegenerative disorder. Parkinson’s Disease is the second most prominent neurodegenerative disease across the world after Alzheimer’s disease. More than 200 years after it was first described by Dr. James Parkinson as “shaking palsy,” the world is still searching for a cure. Currently, the medical intervention is focused mainly on the management of the disease.…